An LAFW cannot be used for compounding an antineoplastic HD (see USP <800> 5.3.2 Sterile Compounding). However, for handling non-antineoplastic and reproductive-risk HDs, each facility may conduct an assessment of risk and implement alternative containment strategies and/or work practices.
An LAFW does not provide a worker with any protection from the HD. A LAFW or CAI may be used for non-antineoplastic HDs. However, alternative containment strategies and/or work practices must be determined during the assessment of risk.